Rheuma Tolerance for Cure (RTCure) is a public-private partnership focusing on earlier detection and prevention of Rheumatoid Arthritis (RA). We wish to change the treatment paradigm from late and unspecific to early and specific. The overarching aim of our project is to prevent RA or its progression by inhibiting the expansion of pathogenic autoimmune responses through immune tolerising treatments. If successful, the type of therapy that RTCure is aiming for, may completely change today's management of RA worldwide, by inducing drug-free remission and removing the need for lifelong treatments in many patients.